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目的:探讨COOK宫颈扩张球囊、地诺前列酮、缩宫素对妊娠期糖尿病孕妇促宫颈成熟的有效性及安全性。方法:回顾分析本院199例促宫颈成熟的妊娠期糖尿病孕妇,其中66例使用COOK宫颈扩张球囊、64例使用地诺前列酮、69例使用缩宫素,比较三组分娩结局及不良反应。结果:球囊组与地诺前列酮组促宫颈成熟有效率、阴道分娩率、引产失败率、用药至临产时间差异无统计学意义(P>0.05),但明显优于缩宫素组(P<0.05);地诺前列酮组宫缩过频率、急产率高于球囊组与缩宫素组(P<0.05),球囊组与缩宫素组差异无统计学意义(P>0.05)。结论:COOK宫颈扩张球囊与地诺前列酮均有较好的促宫颈成熟作用,COOK宫颈扩张球囊安全性更好,建议妊娠期糖尿病孕妇选用COOK宫颈扩张球囊促宫颈成熟
Objective: To investigate the effectiveness and safety of COOK cervical dilatation balloon, dinoprostone and oxytocin on cervical ripening in pregnant women with gestational diabetes mellitus. Methods: A retrospective analysis of 199 cases of pregnant women with cervical ripening of gestational diabetes, 66 patients with COOK cervical dilatation balloon, dilator 64 dronedone, 69 patients with oxytocin, compared three groups of delivery outcomes and adverse reactions . Results: There was no significant difference between the balloon group and the dinoprostone group in promoting cervical ripening rate, vaginal delivery rate, failure rate of induction of labor, medication to labor duration (P> 0.05), but significantly better than oxytocin group (P <0.05). There was no significant difference between the balloon group and the oxytocin group (P> 0.05), the rate of uterine contractions over the dinoprostone group was higher than that of the balloon group and the oxytocin group ). Conclusions: COOK cervical dilatation balloon and dinoprostone have a good role in promoting cervical ripening, COOK cervical dilatation balloon safety is better, it is recommended that gestational diabetes pregnant women choose COOK cervical dilatation balloon to promote cervical ripening