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介绍了一种测定药物释放动力学参数的方法 ,并测定了洗必泰 (Hibitane)和磺胺嘧啶银SD -Ag)的渗透系数P、扩散系数D和膜 -液分配系数K ,为研究药物在丝素膜中的释放动力学规律打下了基础。
A method for determining the kinetic parameters of drug release was introduced. The permeation coefficient P, diffusion coefficient D and membrane-liquid partition coefficient K of Hibitane and SD-Ag were determined. Silk fibroin membrane release kinetics laid the foundation.