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目的研究对胃溃疡合并胃出血的患者采用铝碳酸镁联合奥美拉唑治疗的临床疗效。方法选取78例胃溃疡合并胃出血患者,按照随机数字表达将其分为常规组39例与干预组39例,常规组患者采用奥美拉唑治疗,干预组采用铝碳酸镁联合奥美拉唑治疗,观察两组患者临床疗效及药物不良反应出现情况,观察患者生存质量评分。结果常规组药物不良反应发生率为20.51%,干预组为5.13%,干预组低于常规组,(P<0.05);常规组患者疾病治疗有效率为76.92%,干预组为94.87%,干预组高于常规组(P<0.05)。结论对胃溃疡合并胃出血患者,联合使用奥美拉唑及铝碳酸镁,可有效提高治愈率,减少药物不良反应发生。
Objective To study the clinical efficacy of magnesium aluminum carbonate combined with omeprazole in patients with gastric ulcer and gastric hemorrhage. Methods A total of 78 patients with gastric ulcer and gastric hemorrhage were enrolled. According to the random number expression, they were divided into routine group (n = 39) and intervention group (n = 39). The patients in conventional group were treated with omeprazole. The clinical effects and adverse reactions of the two groups were observed and the quality of life was observed. Results The incidence of adverse drug reactions was 20.51% in the conventional group and 5.13% in the intervention group, which was lower in the intervention group than in the conventional group (P <0.05). The effective rate of disease treatment was 76.92% in the conventional group and 94.87% in the intervention group. Higher than the conventional group (P <0.05). Conclusion In patients with gastric ulcer and gastric hemorrhage, the combination of omeprazole and magnesium aluminum carbonate can effectively improve the cure rate and reduce adverse drug reactions.