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目的探讨腹腔镜下联合垂体后叶素治疗子宫肌瘤可行性及治疗效果。方法腹腔镜下治疗60例子宫肌瘤患者(观察组),予垂体后叶素6U注射入子宫体部,再行剔除手术,与腹腔镜下既往行子宫肌瘤剔除术用缩宫素45例(对照组)比较,分析其手术时间,出血量、肛门排气时间、术后吸收热及住院时间。结果观察组手术时间平均(72.51±3.77)min,短于对照组(108.66±5.87)min;观察组术中出血量平均(50.50±3.05)mL,少于对照组(120.30±4.50)mL;观察组术后肛门排气时间平均(16.71±0.99)h,短于对照组(36.97±0.81)h;观察组术后3d平均体温(37.21±0.08)℃低于对照组(38.21±0.26)℃;观察组术后住院时间平均(3.61±0.49)d,短于对照组(5.46±0.50)d;差异均有统计学意义(P均<0.05)。结论腹腔镜下联合垂体后叶素行子宫肌瘤剔除术止血效果好,安全可行。
Objective To investigate the feasibility and therapeutic effect of laparoscopic combined pituitrin treatment of uterine fibroids. Methods Laparoscopic treatment of 60 patients with uterine fibroids (observation group), pituitary injection of 6U vasopressin into the uterine body, and then removed the operation, and laparoscopic past myomectomy with oxytocin 45 cases (Control group), analyze the operation time, blood loss, anal exhaust time, postoperative absorbed heat and hospitalization time. Results The average operative time in the observation group was (72.51 ± 3.77) min, shorter than that in the control group (108.66 ± 5.87) min. The average intraoperative bleeding volume in the observation group was (50.50 ± 3.05) mL less than that in the control group (120.30 ± 4.50) mL. The time of postoperative anal exhaust was (16.71 ± 0.99) h, shorter than that of the control group (36.97 ± 0.81) h. The mean postoperative 3d temperature of 37.21 ± 0.08 ℃ in the observation group was lower than that of the control group (38.21 ± 0.26) ℃. The average postoperative hospital stay in the observation group was (3.61 ± 0.49) days, which was shorter than that in the control group (5.46 ± 0.50) days. The differences were statistically significant (all P <0.05). Conclusion Laparoscopic combined pituitrin line uterine myomectomy bleeding effect, safe and feasible.