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胰腺癌是高病死率的消化系统恶性肿瘤，手术技术的进步并未明显改善病人预后。随着综合治疗理念的普及，胰腺癌的外科治疗也由“surgery first”进入多学科诊断与治疗协作时代，在术前评估、新辅助治疗及微创技术的应用、术后辅助治疗等方面均取得较大进展。上述治疗的新理念、新方法可在一定程度上改善病人预后，但临床应用还存在争议。如何推动胰腺癌外科治疗向个体化、微创化、精准化方向发展仍是学术界的重要课题。笔者总结近年来多学科诊断与治疗协作理念下胰腺癌外科治疗的新进展，探讨目前其存在的局限和争议，针对胰腺癌外科治疗的未来发展提出思考，以期进一步促进其发展，改善病人预后。“,”Pancreatic cancer is one of the most lethal malignancies in the digestive system, and the prognosis has not been improved with the development of surgery. With the popularization of comprehensive treatment, the surgical treatment of pancreatic cancer has evolved from 'surgery first' stage to the stage of multidisciplinary collaboration in diagnosis and treatment. Great progress has been achieved in pre-operation evaluation, neoadjuvant therapy, minimally invasive surgery and post-operation adjuvant therapy of pancreatic cancer. These novel concepts and methods have improved the prognosis of patients to some extent, but controversies still exist regarding their clinical applications. It is still an important task to establish an individual, minimally invasive and precise treatment system for the surgical treatment of pancreatic cancer. The authors summarize the new progress of surgical treatment of pancreatic cancer under the concept of multiple disciplinary team in recent years, discuss the limitations and controversies, and reflect about the future development of surgical treatment of pancreatic cancer, in order to promote the development of surgical treatment of pancreatic cancer and improve the prognosis of patients.