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急性排斥反应是影响肾移植长期预后的重要因素。在新型免疫抑制剂应用下,急性排斥反应具有表现不典型、难治性排斥反应比例高等特点。本文从发生急性排斥反应高危因素的术前筛查与处理、急性排斥反应早期诊断方法以及对急性排斥反应的干预和免疫抑制药物合理应用、移植后感染预防等方面,综合浙江大学医学院附属第一医院肾脏病中心的临床研究结果,探讨发生急性排斥反应的高危因素、诊断和防控措施,以提高肾移植后长期存活率。
Acute rejection is an important factor that affects the long-term prognosis of renal transplantation. In the application of new immunosuppressive agents, acute rejection has the characteristics of atypical and refractory rejection. This article from the risk factors for acute rejection in preoperative screening and treatment, early diagnosis of acute rejection and acute rejection reaction and the rational use of immunosuppressive drugs, prevention of posttransplant infection, comprehensive Zhejiang University School of Medicine A hospital kidney disease center clinical research results to explore the risk factors for acute rejection, diagnosis and prevention and control measures to improve long-term survival after renal transplantation.