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治疗相关性白血病是指某种疾病经化疗和(或)放疗后继发的白血病。3例银屑病患者经乙双吗啉治疗后发生继发性急性非淋巴细胞性白血病,提示乙双吗啉的诱变性及致白血病性。通过其临床经过的总结,发现此类患者的临床特征与“原发性”急性白血病大致相同,应用适当的治疗方法,此类患者能够获得较好的疗效。结合乙双吗啉的致病机理,提出了继发性白血病的根治方法。
Treatment-related leukemia refers to a disease after chemotherapy and (or) radiotherapy secondary to leukemia. Three cases of psoriasis patients treated with bizomorphine secondary to acute non-lymphocytic leukemia, suggesting that B-morphine mutagenicity and leukemia. Through its clinical summary, found that such patients with clinical features and “primary” acute leukemia is roughly the same, the application of appropriate treatment, such patients can get better efficacy. Combined with the pathogenic mechanism of bicine, put forward the cure of secondary leukemia.