论文部分内容阅读
健康男性志愿受试者22人（其中8名汉族、8名维吾尔族、6名哈萨克族）每人单次回原环丙沙星500mg，用微生物法测定血清浓度比较其体内过程，初步结果表明汉族、维族及哈族T1/2Ke各为3．56±1．01h，2．58±0．37h及2．47±0．25h。在吸收方面，汉族、维族及哈族的Cmax各为2．07±0.43mg／L，2．91±0．38mg／L及3．11±0．40mg／L。Tpeak各为1．49±0．16h，1．13±0．27h及1．11±0．20h，但由于研究对象偏少，尚难得出最后结论，而需进一步考察并论证它在不同民族间引起差异的原因。
A total of 22 healthy volunteers (8 Han, 8 Uygur and 6 Kazakh) returned to ciprofloxacin 500 mg single time each time, and their serum concentrations were measured by the microbial method. The preliminary results showed that Han , Uygur and Kazu T1 / 2Ke each 3.56 ± 1.01h, 2.58 ± 0.37h and 2.47 ± 0.25h. In terms of absorption, Cmax of Han, Uygur and Kazakh were 2.07 ± 0.43mg / L, 2.91 ± 0.38mg / L and 3.11 ± 0.40mg / L, respectively. Tpeak each 1.49 ± 0.16h, 1.13 ± 0.27h and 1.11 ± 0.20h, but due to the small number of subjects, it is difficult to draw the final conclusion, and further investigation and argumentation of it in different ethnic groups Cause the difference between the reasons.