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食物脂肪的原发性消化与吸收障碍能导致脂肪泻,其引起腹泻主要由于脂肪酸抑制结肠液体及电解质的吸收。鉴于需检测粪便脂肪的大多数患者伴有腹泻,本文旨在研究腹泻能否引起粪便脂肪排泄量增加。材料与方法:本组18名正常人(男11,女7,平均年龄30岁)在正常饮食期间连续收集三日粪便,测定其脂肪排泄量。对15名志愿者采用分别口服聚乙烯乙二醇3350、氢氧化镁、乳果糖、山梨醇、硫酸钠或酚酜等诱发渗透性和/或分泌性腹泻,在正常饮食时每日分四次口服指定量的泻药,连服四日,于第2～4日收集粪便,测粪便重量和脂肪含量。结果:18名无腹泻正常人的粪便重量平均122g/日,粪便脂肪排泄量平均3.4g/日,其正常上限6.4g/日。正常人诱发腹泻的48次研究被分为两组,轻至中
Primary digestion and malabsorption of food fats can lead to steatorrhea, which causes diarrhea mainly due to the fatty acid inhibiting colon fluid and electrolyte absorption. In view of the fact that most patients who need to detect fecal fat are accompanied by diarrhea, this article aims to investigate whether diarrhea can cause an increase in excretion of fecal fat. MATERIALS AND METHODS: 18 healthy subjects (male 11, female 7, mean age 30 years) were collected for three consecutive days during the normal diet period to determine their fat excretion. Fifteen volunteers were infused with polyethylene glycol 3350, magnesium hydroxide, lactulose, sorbitol, sodium sulphate or phenolphthalein, respectively to induce osmotic and / or secretory diarrhea. Four times daily during normal diet Oral designated amount of laxatives, and even for four days, collected in the 2nd to 4th feces, fecal weight and fat content measurement. Results: The average fecal weight of 18 normal persons without diarrhea was 122g / day, fecal fat excretion was 3.4g / day on average, and the upper limit of normal was 6.4g / day. 48 studies of normal human induced diarrhea were divided into two groups, light to medium