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[目的]探讨多发性甲状腺结节伴癌变的诊断、术式选择。[方法]回顾性分析2000年1月至2010年1月治疗的456例多发性甲状腺结节伴癌变患者的临床病理特征、手术方式等临床资料。[结果]456例甲状腺多发结节伴甲状腺癌中,合并结节性甲状腺肿、桥本氏病、甲状腺腺瘤等良性疾病伴发乳头状癌431例,占94.5%,滤泡状癌21例,占4.6%,髓样癌4例,占0.9%。[结论]甲状腺结节数目与甲状腺癌无直接关系,不能将结节数目作为判断甲状腺结节是否为癌的依据。对手术切取的结节应常规行术中冰冻病理切片,明确性质以指导手术方式。
[Objective] To investigate the diagnosis and surgical selection of multiple thyroid nodules with carcinogenesis. [Methods] The clinical data of 456 patients with multiple thyroid nodules with carcinogenesis from January 2000 to January 2010 were retrospectively analyzed. [Results] Among 456 thyroid nodules with thyroid cancer, benign diseases such as nodular goiter, Hashimoto’s disease and thyroid adenoma were associated with papillary carcinoma in 431 cases (94.5%) and follicular carcinoma , Accounting for 4.6%, medullary carcinoma in 4 cases, accounting for 0.9%. [Conclusion] The number of thyroid nodules and thyroid cancer are not directly related to the number of nodules can not be used as a basis for judging whether thyroid nodules are cancer. The surgical removal of nodules should be routine frozen intraoperative biopsy, a clear nature to guide the surgical approach.