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目的探讨小剂量阿司匹林联合硫酸镁治疗妊娠期高血压疾病的临床疗效。方法选取2013年3月-2014年3月河北省三河市燕郊人民医院妇产科收治的妊娠期高血压疾病患者220例,随机分为观察组和对照组各110例。观察组给予小剂量阿司匹林联合硫酸镁治疗,对照组单纯给予硫酸镁治疗。治疗后比较2组临床疗效及并发症发生情况。结果治疗后观察组的总有效率为95.5%高于对照组的80.0%,并发症发生率为13.6%低于对照组的24.5%,差异均有统计学意义(P<0.05)。结论小剂量阿司匹林联合硫酸镁治疗妊娠期高血压疾病效果较好,可显著提高临床疗效,减少并发症,值得临床推广应用。
Objective To investigate the clinical efficacy of low-dose aspirin plus magnesium sulfate in the treatment of hypertensive disorder complicating pregnancy. Methods From March 2013 to March 2014, 220 patients with hypertensive disorder complicating pregnancy admitted to Gynecology and Obstetrics Department of Yanjiao People’s Hospital of Sanhe City, Hebei Province were randomly divided into observation group and control group with 110 cases each. The observation group was treated with low-dose aspirin combined with magnesium sulfate, while the control group was treated with magnesium sulfate alone. After treatment, the clinical efficacy and complications of the two groups were compared. Results After treatment, the total effective rate was 95.5% in the observation group and 80.0% in the control group, with a complication rate of 13.6%, which was lower than that of the control group (24.5%, P <0.05). Conclusion Low-dose aspirin combined with magnesium sulfate treatment of hypertensive disorders in pregnancy is better, can significantly improve the clinical efficacy and reduce complications, is worthy of clinical application.