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目的检测在校大学生痤疮患者幽门螺旋杆菌(helicobacter pylori,HP)感染情况,探讨痤疮的发生与幽门螺旋杆菌感染的关系。方法采用C14呼气试验方法对痤疮患者与非痤疮患者进行HP检测和HP阳性率比较,将HP阳性痤疮患者组与HP阳性的非痤疮患者组进行有无胃部症状比较分析,同时将痤疮患者根据症状分级,分析幽门螺旋杆菌感然与痤疮严重程度的关系。结果痤疮患者组HP阳性率(72.00%)明显高于非痤疮患者组HP阳性率(39.23%),HP阳性痤疮患者有胃部症状者(占71.83%)明显多于无胃部症状者(占28.17%),以上差异均有统计学意义。HP阳性非痤疮患者有胃部症状(占47.06%)者低于无胃部症状者(占52.94%),差异无统计学意义。重度痤疮HP阳性率高于轻度痤疮HP阳性率。结论痤疮患者HP检出率高于非痤疮患者;HP阳性病例中有胃部症状痤疮患者病例数高于非痤疮患者;HP阳性与痤疮严重程度相关。提示痤疮的发生与幽门螺旋杆菌感染可能存在关联。因此检测HP以及抗HP感染为痤疮的治疗提供了可能的新方法。
Objective To detect the prevalence of helicobacter pylori (HP) infection among college students with acne and to explore the relationship between the incidence of acne and Helicobacter pylori infection. Methods The C14 breath test was used to detect the HP of acne patients and non-acne patients. The positive rate of HP was compared between HP positive acne patients and non-acne patients without HP. The patients with acne According to the symptom grade, the relationship between Helicobacter pylori and acne severity was analyzed. Results The positive rate of HP in patients with acne (72.00%) was significantly higher than that in non-acne patients (39.23%). The patients with acne vulgaris had more stomach symptoms (71.83%) than those without stomach symptoms 28.17%), the above differences were statistically significant. There was no statistically significant difference between the HP-positive and non-acne patients with stomach symptoms (47.06%) and with no stomach symptoms (52.94%). Severe acne HP positive rate higher than mild acne HP positive rate. Conclusion The detection rate of HP in patients with acne is higher than that in non-acne patients. The number of acne patients with gastric symptoms in HP positive cases is higher than that in non-acne patients. The positive of HP is related to the severity of acne. Tip Acne and Helicobacter pylori infection may be related. So detecting HP and anti-HP infection provides a new possible method for the treatment of acne.