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目的:探究分析纳洛酮治疗Ⅱ型呼吸衰竭肺性脑病的临床效果。方法:根据住院单双号将随机抽取的88例Ⅱ型呼吸衰竭肺性脑病患者划分为对照组和观察组,对照组给予常规治疗,观察组在对照组治疗基础上添加纳洛酮进行治疗,对比分析两组临床效果。结果:通过治疗,观察组临床总有效率明显高于对照组,同时pH值、动脉氧分压、血氧饱和度高于对照组,且动脉二氧化碳分压低于对照组(P<0.05)。结论:采用纳洛酮治疗Ⅱ型呼吸衰竭肺性脑病能够明显提高临床效果,快速优化血气指标,缓解二氧化碳潴留,逆转肺性脑病进程,用药安全。
Objective: To investigate the clinical effect of naloxone on pulmonary encephalopathy in type Ⅱ respiratory failure. Methods: According to the single and double hospitalization, 88 patients with pulmonary encephalopathy of type Ⅱ respiratory failure were randomly divided into the control group and the observation group. The control group was given routine treatment. The observation group was treated with naloxone on the basis of the control group, Comparative analysis of two groups of clinical results. Results: The total clinical effective rate in the observation group was significantly higher than that in the control group. Meanwhile, the values of pH, arterial oxygen pressure and oxygen saturation were higher than those of the control group, and the arterial carbon dioxide partial pressure was lower than that of the control group (P <0.05). Conclusion: Naloxone treatment of pulmonary encephalopathy Ⅱ respiratory failure can significantly improve clinical efficacy, rapid optimization of blood gas index, relieve carbon dioxide retention, reversal of pulmonary encephalopathy process, medication safety.