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目的评价卡托普利对冠状动脉扩张症的疗效。方法将冠状动脉造影证实为冠状动脉扩张的稳定性心绞痛患者,患者总数40例,随机分为硝酸异山梨酯组和卡托普利组,疗程1年,观察心绞痛发作、平板运动试验、冠状动脉造影等项的影响。结果治疗后卡托普利组总有效率87.5%,硝酸异山梨酯组总有效率17.7%,两组对比有显著差异,P<0.05。结论卡托普利治疗冠状动脉扩张中明显改善平板运动试验的结果,减少心绞痛的发病,冠脉血流明显改善,所以卡托普利是治疗冠状动脉扩张的有效药物。
Objective To evaluate the efficacy of captopril in patients with coronary artery dilatation. Methods A total of 40 patients with stable angina pectoris who underwent coronary angiography were randomly divided into isosorbide dinitrate group and captopril group. The course of treatment was one year. Angina pectoris, treadmill exercise test, coronary artery Contrast and other items of influence. Results After treatment, the total effective rate was 87.5% in captopril group and 17.7% in isosorbide dinitrate group. There was significant difference between the two groups (P <0.05). Conclusion Captopril treatment of coronary artery dilatation significantly improved the results of treadmill exercise test to reduce the incidence of angina pectoris, coronary blood flow significantly improved, so captopril is an effective drug for the treatment of coronary artery dilatation.