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急性肾损伤(AKI)在全球范围内流行,且发病率不断增高。其中药物相关性AKI所占比例逐渐增加,已成为住院患者AKI发生的重要原因。AKI的发生明显加重患者病情并增加死亡的风险。新型标志物有利于药物相关性AKI的早期识别。早期识别AKI易发人群,合理选择和使用药物,制定个体化处方,预防和及时治疗是AKI管理工作中的重要任务。
Acute kidney injury (AKI) is prevalent worldwide with an increasing incidence. Among them, the proportion of drug-related AKI gradually increased, which has become an important reason for the occurrence of AKI in hospitalized patients. The occurrence of AKI significantly aggravates the patient’s condition and increases the risk of death. Novel markers favor the early identification of drug-related AKI. Early identification of AKI susceptible populations, rational selection and use of drugs, the development of individual prescriptions, prevention and timely treatment is an important task in the management of AKI.