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目的:探讨地屈孕酮与黄体酮在先兆流产患者治疗中的疗效对比。方法:将2015年1月至2016年1月在我院妇科治疗的120例先兆流产患者随机分为两组,观察组采用口服地屈孕酮治疗,对照组采用肌注黄体酮治疗,比较两组患者的保胎成功率、症状消失时间、孕酮值及不良反应等。结果:观察组保胎成功率为95%,明显高于对照组的88.33%(P<0.05);观察组症状消失时间明显较对照组短,而孕酮值明显高于对照组(P<0.05);观察组恶心、头痛等不良反应发生率明显低于对照组(P<0.05)。结论:地屈孕酮较黄体酮治疗先兆流产效果更佳,且服用方便,不良反应低,更适合临床使用。
Objective: To compare the therapeutic effect of dydrogesterone and progesterone in the treatment of threatened abortion. Methods: One hundred and twenty cases of threatened abortion underwent gynecological treatment in our hospital from January 2015 to January 2016 were randomly divided into two groups. The observation group received oral dydrogesterone treatment while the control group received intramuscular injection of progesterone. The success rate of miscarriage, symptom disappear time, progesterone value and adverse reactions in the group of patients. Results: The success rate of miscarriage in the observation group was 95%, which was significantly higher than that in the control group (88.33%, P <0.05). The symptom disappearance time in the observation group was shorter than that in the control group, while the progesterone level was significantly higher than that in the control group ). The adverse reaction rate of nausea and headache in observation group was significantly lower than that in control group (P <0.05). Conclusion: Dydrogesterone is more effective than progesterone in the treatment of threatened abortion, and it is convenient to take and has low adverse reactions. It is more suitable for clinical use.