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目的:探讨桂枝附子汤对佐剂性关节炎大鼠血清白介素-6水平的影响。方法:通过比较各组大鼠血清中IL-6的含量来考察桂枝附子汤的疗效。结果:血清中IL-6的含量,桂枝附子汤组与模型组比较有显著性差异(P<0.01)。结论:桂枝附子汤能降低佐剂性关节炎大鼠血清中IL-6的含量,对类风湿关节炎有治疗作用。
Objective: To investigate the effect of Guizhifuzi Decoction on serum interleukin-6 level in adjuvant arthritis rats. Methods: The efficacy of Guizhifuzi Decoction was investigated by comparing the serum levels of IL-6 in each group. Results: The content of IL-6 in serum was significantly different between Guizhifuzi Decoction group and model group (P <0.01). Conclusion: Guizhi aconite decoction can reduce the content of IL-6 in the serum of adjuvant arthritis rats and has the therapeutic effect on rheumatoid arthritis.