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目的：观察有髓鞘纤维病变与三叉神经痛之间的关系。方法：用透射电镜观察10例三叉神经痛患者痛支与非痛支神经及5例无三叉神经痛口腔颌面部肿瘤手术患者舌神经、眶下神经及耳大神经。结果：10例三叉神经痛患者的痛支及非痛支神经的有髓鞘纤维均有明显的病理改变，主要是神经膜细胞（雪旺细胞）、髓鞘、线粒体的病变；5例无三叉神经痛的手术患者中仅1例年龄最大者，舌神经出现与三叉神经痛患者类似的病变。结论：有髓鞘纤维的病变与三叉神经痛有一定的关系，可能是发病因素之一；有髓鞘纤维的病变可能是一种增龄性变化；在有髓鞘纤维病变的基础上，是否发病还与其他因素有关。
Objective: To observe the relationship between myelinated fibrosis and trigeminal neuralgia. Methods: Ten cases of painful and non-painful nerves in patients with trigeminal neuralgia and five patients with lingual nerve, infraorbital nerve and auricle nerves in operation of oral and maxillofacial tumors without trigeminal neuralgia were observed by transmission electron microscopy. Results: All the 10 cases of trigeminal neuralgia had obvious pathological changes of the painful branches and the myelinated fibers of non-painful nerves, which were mainly the lesions of Schwann cells, myelin sheaths and mitochondria; Only 1 of the patients with neuralgia underwent surgery, the lingual nerve with similar lesions in patients with trigeminal neuralgia. Conclusion: There is a certain relationship between myelinated fibers and trigeminal neuralgia, which may be one of the risk factors. Myelinated fibers may be an age-related change. On the basis of myelinated fibers, is The incidence is also related to other factors.