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目的:观察健脾益肾方联合西药治疗骨质疏松症的临床疗效。方法:选取90例脾肾亏虚型骨质疏松症患者,随机分为对照组和治疗组各45例,2组均以常规药物进行治疗,治疗组在此基础上加用健脾益肾方,2组均连续治疗3月,比较2组的临床疗效,观察治疗前后血钙、血磷、碱性磷酸酶及骨密度的变化。结果:总有效率对照组为73.3%,治疗组为95.6%,治疗组总有效率高于对照组(P<0.01);治疗后,2组血钙水平均较治疗前升高(P<0.05),治疗组升高较对照组显著(P<0.05);2组碱性磷酸酶均较治疗前下降(P<0.05),治疗组降低更为显著(P<0.05);2组L2~4、股骨颈及股骨粗隆的骨密度均较治疗前增加(P<0.05),治疗组3处骨密度的增加均较对照组显著(P<0.05)。结论:在常规治疗的基础上加用健脾益肾方治疗脾肾亏虚型骨质疏松症患者,可明显改善患者的血钙、碱性磷酸酶水平,增加骨密度,提高临床治疗效果。
Objective: To observe the clinical efficacy of “Jianpi Yishen Recipe” combined with western medicine in the treatment of osteoporosis. Methods: 90 cases of spleen and kidney deficiency type of osteoporosis were randomly divided into control group and treatment group of 45 cases, two groups were treated with conventional drugs, the treatment group on this basis with the spleen and kidney prescription , Two groups were continuous treatment for 3 months, compared the clinical efficacy of two groups, observed before and after treatment of serum calcium, phosphorus, alkaline phosphatase and bone mineral density changes. Results: The total effective rate was 73.3% in the control group and 95.6% in the treatment group. The total effective rate in the treatment group was higher than that in the control group (P <0.01) ) In the treatment group was significantly higher than that in the control group (P <0.05). The levels of alkaline phosphatase in the two groups were significantly lower than those before treatment (P <0.05) , Femoral neck and femur trochanter increased compared with those before treatment (P <0.05). The BMD of three treatment groups was significantly higher than that of the control group (P <0.05). Conclusion: The treatment of Spleen and Kidney Deficiency Osteoporosis with Jianpi Yishen Recipe on the basis of routine treatment can significantly improve the levels of serum calcium and alkaline phosphatase, increase the bone mineral density and improve the clinical therapeutic effect.