地方性氟中毒侵犯全身各组织器官,是一种全身性慢性疾病,损害主要表现在牙齿和骨骼上。骨骼损害为腰腿痛,全身关节疼痛,关节活动受限,骨骼变坏,弯腰驼背,严重者卧床不起甚至瘫痪[1]。粤北始兴地处粤北山区,地质构造复杂与特殊,含有丰富温泉水资源和富氟岩石,致使部分自然村居民 Local fluorosis invades the various tissues and organs of the body and is a generalized chronic disease that damages mainly in the teeth and bones. Skeletal injury is low back pain, general joint pain, limited joint activity, deterioration of bones, hunched over, severe cases of bed rest and even paralysis [1]. Shixing, northern Guangdong is located in northern Guangdong mountainous area, geological structure is complex and special, rich in hot spring water and fluoride-rich rock, resulting in some natural village residents