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据2016年4月29日《科技日报》报道,中科院昆明动物所孔燕杰等发现,从中国传统药用植物绿升麻的干燥块茎中分离纯化出的三萜类单体活性化合物KHF16能够显著抑制三阴性乳腺癌细胞系;KHF16是部分地通过抑制三阴性乳腺癌细胞增殖和存活相关信号通路,来诱导癌细胞的凋亡和周期阻滞、降低耐药蛋白的表达水平,从而达成抑制癌细胞增
According to a report by the Science and Technology Daily of April 29, 2016, Kong Yanjie of Kunming Institute of Zoology, Chinese Academy of Sciences, found that the triterpene monomeric active compound KHF16 isolated and purified from the dried tuber of Chinese traditional medicinal plant Cinnamomum can significantly inhibit three The negative breast cancer cell line; KHF16 induces apoptosis and cycle arrest and reduces the expression level of drug resistance proteins in part by inhibiting the proliferation and survival related signaling pathways of triple negative breast cancer cells, thereby achieving suppression of cancer cell growth