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目的探讨补锌制剂在治疗小儿腹泻中的临床疗效。方法选取6个月~4岁之间的腹泻患儿,共108例,随机分为试验组和对照组,各54例。2组患儿均给予对症综合治疗,试验组在对症治疗的基础上再辅助补锌制剂进行治疗。对2组患儿的止泻时间、不良症状消失时间、治疗效果等进行观察和比较。结果试验组的止泻时间平均为(3.02±0.48)d,显著优于对照组的[(4.15±1.60)d](P<0.05);发热消失平均时间为(2.10±1.02)d,呕吐消失平均时间为(1.00±0.47)d,均显著短于对照组的[(3.12±1.35)d]、[(1.56±0.69)d](P<0.05);试验组总有效率为96.30%,对照组总有效率为83.33%,2组比较差异有统计学意义(P<0.05)。结论补锌制剂对于辅助治疗小儿腹泻具有较好的作用机制,能够显著改善患儿的腹泻症状,有利于提高临床疗效,且操作方法简便,值得临床推广。
Objective To investigate the clinical efficacy of zinc supplementation in the treatment of children with diarrhea. Methods A total of 108 children with diarrhea aged 6 months to 4 years were randomly divided into experimental group and control group, with 54 cases in each group. Two groups of children were given symptomatic comprehensive treatment, the experimental group on the basis of symptomatic treatment and then assisted with zinc preparations for treatment. Two groups of children with diarrhea time, the disappearance of adverse symptoms, treatment effects were observed and compared. Results The average diarrhea time of the experimental group was (3.02 ± 0.48) d, which was significantly better than that of the control group [(4.15 ± 1.60) d] (P <0.05). The average duration of disappearance of fever was (2.10 ± 1.02) days and vomiting disappeared The mean effective time was (1.00 ± 0.47) d, which was significantly shorter than that of the control group [(3.12 ± 1.35) d] and [(1.56 ± 0.69) d], respectively The total effective rate was 83.33%. There was significant difference between the two groups (P <0.05). Conclusion The zinc supplement has a good mechanism for adjuvant treatment of children with diarrhea, which can significantly improve the symptoms of children with diarrhea, improve the clinical curative effect, and the operation method is simple and worthy of clinical promotion.