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目的探讨苯磺酸氨氯地平片治疗社区高血压的临床疗效。方法 98例高血压患者,随机分为对照组和研究组,各49例。对照组采用硝苯地平片治疗,研究组采用苯磺酸氨氯地平片治疗。观察两组治疗效果。结果两组患者治疗前血压水平比较差异无统计学意义(P>0.05);治疗8周后两组患者的血压均低于治疗前,且研究组患者的血压明显低于对照组,差异有统计学意义(P<0.05)。研究组临床总有效率为95.92%,高于对照组的83.67%,差异有统计学意义(P<0.05)。研究组患者不良反应发生率为2.04%,低于对照组患者的14.29%,差异有统计学意义(P<0.05)。结论社区高血压应用苯磺酸氨氯地平片治疗具有十分显著的临床疗效,能够有效降低患者血压,不良反应少,值得在临床上大力推广应用。
Objective To investigate the clinical efficacy of amlodipine besylate in the treatment of community-based hypertension. Methods 98 patients with hypertension were randomly divided into control group and study group, 49 cases in each. The control group was treated with nifedipine tablets and the study group was treated with amlodipine besylate tablets. Observation of two groups treatment effect. Results There was no significant difference in blood pressure before treatment between the two groups (P> 0.05). After 8 weeks of treatment, the blood pressure of the two groups was lower than before treatment, and the blood pressure of the study group was significantly lower than that of the control group Significance (P <0.05). The total clinical effective rate was 95.92% in the study group, which was higher than that in the control group (83.67%), the difference was statistically significant (P <0.05). The incidence of adverse reactions in study group was 2.04%, which was lower than that in control group (14.29%), the difference was statistically significant (P <0.05). Conclusion The application of amlodipine besylate in community hypertension has significant clinical curative effect, can effectively reduce the blood pressure of patients, and has few adverse reactions. It is worth to be widely applied clinically.