AIM:To study the impact of scleral flap position,under which the posterior chamber intraocular lenses(PC-IOL) were sulcus-fixed by trans-scleral suture,on cornea astigmatism.METHODS:Twenty-six aphakic or cataract eyes were comprised in this prospective noncomparative case series study.Eleven eyes had traumatic cataract removed without sufficient capsular support,3 had blunt trauma with subluxated traumatic cataract,8 had undergone vitreoretinal surgery and 4 had congenital cataract removed.The average age was 54 years(range 21-74 years),with 17 men and 7 women.The foldable PC-IOL was fixed in sulcus by trans-scleral suture.The incision for IOL implantation was made 1mm posterior to limbus along the steepest meridian of cornea,while scleral flaps to bury the knots of trans-scleral suture were made along the flattest meridian.All the surgeries were performed by a single doctor(Ma L),and the follow up was at least 13 months(range 13-28 months).The preoperative,3 months and 1 year postoperative corneal curvature along the steepest and flattest cornea meridian and overall cornea astigmatism were compared.RESULTS:The curvature along the steepest meridian changed from 44.25±2.22D preoperatively to 44.08±2.16D at 3 months postoperatively,and 43.65±5.23D at 1 year postoperatively(P >0.05);the curvature along the flattest meridian changed from 41.24±2.21D preoperatively to 43.15±3.94D at 3 months postoperatively,and 42.85±5.17D at 1 year postoperatively(P <0.05);and the surgery induced astigmatism(SIA) on cornea was calculated by vector analysis,which was 2.42±2.13D at 3 months postoperatively,and 2.18±3.42D at 1 year postoperatively,the difference was statistically significant(P <0.05).CONCLUSION:The scleral flap made along the flattest meridian,under which the posterior chamber intraocular lenses(PCIOL) were sulcus-fixed by trans-scleral suture,can steepen the cornea in varying degrees,thus reducing preexisting corneal astigmatism. AIM: To study the impact of scleral flap position, under which the posterior chamber intraocular lenses (PC-IOL) were sulcus-fixed by trans-scleral suture, on cornea astigmatism. METHODS: Twenty-six aphakic or cataract eyes were were in this prospective noncomparative case series study. Eleven eyes had traumatic cataract removed without sufficient capsular support, 3 had blunt trauma with subluxated traumatic cataract, 8 had undergone vitreoretinal surgery and 4 had congenital cataract removed. average age was 54 years (range 21-74 years ), with 17 men and 7 women. The foldable PC-IOL was fixed in sulcus by trans-scleral suture. incision for IOL implantation was made 1mm posterior to limbus along the steepest meridian of cornea, while scleral flaps to bury the knots of trans-scleral suture were made along the flattest meridian. All the surgeries were performed by a single doctor (Ma L), and the follow up was at least 13 months (range 13-28 months). The preoperative, 3 months and 1 year postoper ative corneal curvature along the steepest and flattest cornea meridian and overall cornea astigmatism were compared. RESULTS: The curvature along the steepest meridian changed from 44.25 ± 2.22D preoperatively to 44.08 ± 2.16D at 3 months postoperatively, and 43.65 ± 5.23D at 1 year postoperatively (P> 0.05); the curvature along the flattest meridian changed from 41.24 ± 2.21D preoperatively to 43.15 ± 3.94D at 3 months postoperatively, and 42.85 ± 5.17D at 1 year postoperatively (P <0.05); and the surgery induced astigmatism (SIA) on cornea was calculated by vector analysis, which was 2.42 ± 2.13D at 3 months postoperatively, and 2.18 ± 3.42D at 1 year postoperatively, the difference was statistically significant (P <0.05). CONCLUSION: The scleral flap made along the flattest meridian, under which the posterior chamber intraocular lenses (PCIOL) were sulcus-fixed by trans-scleral suture, can steepen the cornea in varying degrees, thereby reducing preexisting corneal astigmatism.