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目的 研究同种生精干细胞移植的后的形态学变化。方法 在不采用免疫抑制剂的条件下 ,在基因型相似的封闭群昆明白小鼠间进行同种生精干细胞移植 ,移植后 3个月 ,观察其生精恢复情况。结果 形态学证实 ,成功移植的小鼠生精功能基本恢复正常。结论 在基因型类似的昆明白小鼠进行同种生精干细胞移植是可行的。
Objective To study the morphological changes of allogeneic stem cells after transplantation. Methods Spermatogenic stem cell transplantation was performed in Kunming white mice of similar genotypes without immunosuppressive agents. The recovery of spermatogenesis was observed 3 months after transplantation. Morphological results confirmed that the successful implantation of mice spermatogenic function returned to normal. Conclusion Allogenic spermatogenic stem cell transplantation is feasible in Kunming white mice with similar genotypes.