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目的:研究十二指肠溃疡(Duodenal ulcer,DU)患者幽门螺杆菌(Helicobacter pylori,HP)感染与胃排空功能的关系。方法:根据Giemsa染色与快速尿素酶检测结果76例经胃镜证实的DU分为HP阴性(27例)和HP阳性(49例)两组。健康对照组13例。用99mTc标记法对以上3组对象进行液体与固体胃排空检查。结果:①HP阴性组、阳性组和健康组年龄无差异,HP阴性与阳性溃疡组在溃疡病程、溃疡大小、吸烟、饮酒、出血史、家族史上无差异,但吸烟与饮酒者的比例均高于对照组。②3组液体与固体半排时间(T1/2)无差异。③各时点 3组液体与固体排空率无差异。④3组固体排空迟滞相无差异。结论:①DU患者胃排空功能与健康人相似。②HP阴性与阳性的DU胃排空功能一致。
Objective: To study the relationship between Helicobacter pylori (HP) infection and gastric emptying in patients with Duodenal ulcer (DU). Methods: According to Giemsa stain and rapid urease test, 76 cases of DU confirmed by gastroscope were divided into two groups: HP negative (27 cases) and HP positive (49 cases). Healthy control group of 13 cases. 99mTc labeling method for the above three groups of liquid and solid gastric emptying examination. Results: ①HP negative group, positive group and healthy group no difference in age, HP negative and positive ulcer group in the ulcer course, ulcer size, smoking, drinking, history of bleeding, family history no difference, but the proportion of smoking and drinking were higher than Control group. ② There was no difference in liquid and solid half row time (T1 / 2) in group 3. (3) There was no difference in the emptying rate of liquid and solid between the three groups at all time points. ④ There is no difference between the three groups of solid emptying hysteresis phase. Conclusion: ① DU patients with gastric emptying function similar to healthy people. ②HP negative and positive DU gastric emptying function.