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目的:探究腺垂体功能减退症及其危象的临床表现及诊治效果。方法:随机选取2015年1月-2016年12月本院收治的68例腺垂体功能减退症及其危象患者作为观察对象,回顾性地对所有患者的基本临床资料进行研究分析。结果:68例腺垂体功能减退症及其危象患者中,临床诊断出2例(2.94%)自体免疫性垂体炎,14例(20.59%)颅咽管术后放疗,32例(47.06%)席汉氏综合征,4例(5.88%)空泡蝶鞍,16例(23.53%)垂体瘤。经临床治疗后,60例(88.24%)患者抢救成功,其余8例(11.76%)患者死亡,总体治疗效果比较满意。结论:临床中不明原因嗜睡、乏力、性欲减退或者毛发脱落等症状均可作为腺垂体功能减退症及其危象患者的征兆,尽早采用有效方法对其进行诊断与治疗可以有效降低误诊率,提高临床疗效。
Objective: To investigate the clinical manifestations and diagnosis and treatment of hypopituitarism and its crisis. Methods: A total of 68 patients with hypopituitarism and its crisis who were treated in our hospital from January 2015 to December 2016 were randomly selected as the observation subjects. The clinical data of all patients were retrospectively analyzed. Results: Among the 68 patients with hypopituitarism and its crisis, 2 cases (2.94%) had autoimmune hypophysitis, 14 cases (20.59%) had craniopharyngioma postoperative radiotherapy, and 32 cases (47.06% Sheehan’s syndrome, 4 cases (5.88%) vacuolar sella, 16 cases (23.53%) pituitary tumor. After clinical treatment, 60 patients (88.24%) were successfully rescued, and the remaining 8 patients (11.76%) died. The overall treatment effect was satisfactory. Conclusion: The symptoms such as unexplained lethargy, fatigue, loss of libido or hair loss can be used as signs of pituitary hypogonadism and its crisis in the clinic. Early effective diagnosis and treatment can effectively reduce the rate of misdiagnosis and increase the rate of misdiagnosis Clinical efficacy.