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目的:分析不同促排卵方案对夫精人工授精(IUI)导管排气周期妊娠率的影响,为提高IUI周期妊娠率提供依据。方法:将200例不孕症患者进行的417个周期随机分为排气组(221周期)与未排气组(196周期),比较四种不同促排卵方案:枸橼酸氯米芬促排卵组(CC组)、尿促性腺激素促排卵组(HMG组)、枸橼酸氯米芬+尿促性腺激素促排卵组(CC+HMG组)、自然周期组(NC组)对IUI导管排气周期妊娠率的影响。结果:417个IUI周期共有50例临床妊娠,总周期妊娠率为11.99%。其中CC组、CC+HMG组对IUI导管排气周期妊娠率的影响差异有统计学意义(P<0.05),而NC组、HMG组对IUI导管排气周期妊娠率的影响差异无统计学意义(P>0.05)。结论:不同促排卵方案结合IUI导管排气对提高IUI周期妊娠率是有一定临床指导意义的。
OBJECTIVE: To analyze the effect of different ovulation induction programs on the pregnancy rate of IUD catheter exhaust cycle, and provide the basis for improving IUI cycle pregnancy rate. Methods: Four hundred and seventy cycles of infertility were randomly divided into two groups (221 cycles) and 196 cycles (cycles 196 cycles). Four different ovulation induction schedules were compared: clomiphene citrate ovulation induction (CC group), ovarian gonadotropin ovulation group (HMG group), clomiphene citrate + urinary gonadotropin ovulation group (CC + HMG group) and natural period group (NC group) Effect of gas cycle pregnancy rate. Results: There were 50 clinical pregnancies in 417 IUI cycles with a total cycle pregnancy rate of 11.99%. There was significant difference between the CC group and the CC + HMG group in the IUC catheter exhaust cycle pregnancy rate (P <0.05), while there was no significant difference between the NC group and the HMG group in the IUC catheter exhaust cycle pregnancy rate (P> 0.05). Conclusion: Different ovulation induction programs combined with IUI catheter exhaust have some clinical significance in improving the IUP cycle pregnancy rate.