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目的观察优泌乐50治疗老年2型糖尿病的有效性及安全性。方法选择48例口服降糖药物失效的老年2型糖尿病患者随机分为两组,A组为优泌乐50组,B组为优泌林70/30组,治疗12周,观察治疗前后两组患者空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1 c)、血糖达标时间、胰岛素用量、低血糖发生率等指标。结果两组经治疗后空腹血糖控制水平相似,均较入院时显著下降,但组间差异无统计学意义(P>0.05);A组2 hPG、HbA1 c较B组下降明显,血糖达标时间短,胰岛素用量少,低血糖发生率低。结论优泌乐50治疗老年2型糖尿病安全、有效,依从性好。
Objective To observe the efficacy and safety of Uehara 50 in the treatment of type 2 diabetes in the elderly. Methods Forty-eight elderly patients with type 2 diabetes who were treated with oral glucose-lowering drugs were randomly divided into two groups: group A was 50, and group B was group Euurin 70/30. After 12 weeks of treatment, Fasting blood glucose (FPG), postprandial 2h blood glucose (2hPG), glycosylated hemoglobin (HbA1c), blood glucose compliance time, insulin dosage, the incidence of hypoglycemia and other indicators. Results The fasting blood glucose levels after treatment were similar in both groups, which were significantly lower than those at admission, but there was no significant difference between the two groups (P> 0.05). The levels of HbA1c and 2hPG in group A were significantly lower than those in group B , Less insulin, low incidence of hypoglycemia. Conclusion Youji 50 in the treatment of elderly with type 2 diabetes is safe, effective, and good compliance.