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目的探讨超声检查对伴周边环形钙化良恶性甲状腺结节的诊断价值。方法选取58例伴周边环形钙化甲状腺结节患者,根据临床病理学检测结果将其分为良性组(良性甲状腺结节,44例)和恶性组(恶性甲状腺结节,14例)。比较两组患者周边环形钙化良恶性甲状腺结节的一般情况和超声诊断结果。结果两组患者甲状腺结节最大径、边界清晰度、内部回声等一般资料比较差异未见统计学意义(P>0.05);两组间钙化厚薄和钙化连续性比较差异有统计学意义(P<0.05),钙化周围声晕比较差异未见统计学意义(P>0.05)。钙化厚薄不均匀诊断恶性甲状腺结节的阳性预测值为46.15%(6/13),阴性预测值为82.22%(37/45);钙化连续性中断诊断恶性甲状腺结节的阳性预测值为41.67%(10/24),阴性预测值为88.24%(30/34)。结论超声检查中甲状腺结节周围环形钙化厚薄是否均匀、钙化连续性是否中断可作为诊断良恶性甲状腺结节的重要指标。
Objective To investigate the diagnostic value of ultrasonography in benign and malignant thyroid nodules with peripheral annular calcification. Methods Fifty - eight patients with peripheral annular calcified thyroid nodules were divided into benign thyroid nodules (n = 44) and malignant thyroid nodules (n = 14) according to the results of clinicopathological examination. The general situation and ultrasound diagnosis results of benign and malignant thyroid nodules around the annular calcification in two groups were compared. Results There was no significant difference in the general data of maximum diameter of thyroid nodules, border articulation and internal echo between the two groups (P> 0.05). There was significant difference between the two groups in the thickness of calcification and the continuity of calcification (P < 0.05), there was no significant difference in the sound halo around calcification (P> 0.05). The positive predictive value of malignant thyroid nodules with non-uniform calcification thickness was 46.15% (6/13) and the negative predictive value was 82.22% (37/45). The positive predictive value of malignant thyroid nodules with discontinuity of calcification was 41.67% (10/24), the negative predictive value was 88.24% (30/34). Conclusion Ultrasound examination of thyroid nodules around the annular calcification thickness is uniform, whether the interruption of calcification continuity can be used as an important indicator of benign and malignant thyroid nodules.