新生儿溶血病(HDN)是由于母婴血型不合而引起的同族血型免疫性疾病,可发生于胎儿和新生儿早期。胎儿由父亲方面遗传抗原而恰为母亲所缺少,此抗原侵入母体,刺激母体而产生免疫抗体,此抗体可经过胎盘进入胎儿血循环,胎儿红细胞与相应抗体结合而大量溶血造成贫血,大多数病例出生时与正常新生儿相似,并无明显的贫血水肿 Neonatal hemolytic disease (HDN) is a congenial blood group immunity disorder caused by maternal-fetal incompatibility, which can occur in the fetus and early neonates. The fetus by the father of genetic antigen and just missing for the mother, the antigen invades the mother to stimulate the mother to produce immune antibodies, this antibody can be passed through the placenta into the fetal blood circulation, fetal red blood cells and the corresponding antibodies and a large number of hemolysis caused by anemia, most cases were born When normal newborns, there is no obvious anemia and edema