老年乳腺癌193例临床病理分析

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本文报告60岁以上老人乳腺癌193例。其中女性182例,男性11例。女、男之比为16.5∶1。发病年龄为60~91岁。其中60~69岁为171例,占88.6%。70岁以上者22例,占11.4%。本组病例均为已婚男、女,其中未生育者23例,其余均为有生育能力的妇女。生育5胎以上者91例,占50%(91/182)。50岁以上闭经者占57.1%,平均闭经年龄52.7岁,显示多生育者及闭经晚者易患乳腺癌。老年乳腺癌病程长,最长达480个月,一年之内确诊只占46.6%,平均确诊时间为35.5个月。老年乳腺癌并发疾病多,193例中79例合并不同疾病,如糖尿病、高血压、冠心病等。一年之内死亡的40例中,除9例死于癌症晚期外,其余31例均死于并发病。本组病例1、3、5年生存率分别为79.3%、67.4%、48.7%。单纯手术组133例,合并化,放疗组60例,化、放疗综合治疗并没有提高生存期。我们认为老年乳腺癌治疗应以手术为主加激素治疗的综合治疗措施。 This article reports 193 cases of breast cancer in the elderly over the age of 60. There were 182 females and 11 males. The ratio of female to male is 16.5:1. The age of onset is 60 to 91 years old. Among them, 171 cases aged 60 to 69 accounted for 88.6%. Twenty-two patients over the age of 70 accounted for 11.4%. The patients in this group were married males and females, of whom 23 were not born and the rest were women with fertility. Ninety-one children had more than 5 births, accounting for 50% (91/182). The rate of amenorrhea among those over the age of 50 accounted for 57.1%, and the average amenorrhea age was 52.7 years. This indicates that multiple births and late amenorrhea are susceptible to breast cancer. Elderly breast cancer has a long duration of up to 480 months. Within a year, the diagnosis is only 46.6%. The average diagnosis time is 35.5 months. There were many complications of breast cancer in the elderly, 79 of 193 cases were associated with different diseases such as diabetes, hypertension, and coronary heart disease. Of the 40 cases that died within a year, except 9 cases who died of advanced cancer, the remaining 31 cases died of complications. The 1, 3, and 5-year survival rates in this group were 79.3%, 67.4%, and 48.7%, respectively. There were 133 cases in the simple surgery group, 60 cases in the combined and radiotherapy group, and comprehensive treatment with chemotherapy and radiotherapy did not improve the survival period. We believe that the treatment of elderly breast cancer should be based on the combination of surgery and hormone therapy.
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