肿瘤细胞对多种化学药物产生交叉耐药性 ,称多药耐药 (ＭＤＲ) ,是造成肿瘤化学药物治疗 (化疗 )失败的主要原因。统计表明 ,肿瘤年死亡率中 ,属内在性多药耐药 (ｉｎｔｒｉｎｓｉｃＭＤＲ)的肿瘤 ,包括消化器官、呼吸系统、泌尿系统以及中枢神经系统肿瘤引起的约占 6 1% ;属获 Tumor cells cross-resistance to a variety of chemical drugs, called multidrug resistance (MDR), is the main reason for the failure of cancer chemotherapy (chemotherapy). Statistics show that among the annual tumor mortality, an intrinsic MDR tumor, which includes digestive organs, respiratory system, urinary system, and central nervous system tumors, accounts for about 61%;