【《医学世界报导》1989年2月】吸烟与骨质疏松之间的关系长期受到人们的怀疑,目前已发现有更多的证据表明二者有关。法国阿尔贡国家实验室的一位生化学家 MarykaBhattacharyya 称,含大量镉的饲料可使怀孕的大鼠和卵巢已被切除的大鼠,骨质明显丢失,但镉对雄性大鼠和非怀孕的雌性大鼠则影响很少。众所周知,烟草中含有镉这种重金属。体外的实验亦发现把镉加至细胞培养物中,骨质发生明显丢失。流行病学家早已证明吸烟是造成骨质疏松的一个危险因素,但迄今在 Medical World Report, February 1989 The relationship between smoking and osteoporosis has long been suspected by people and more evidence has been found that they are related. MarykaBhattacharyya, a biochemist at the Argonne National Laboratory in France, said that large amounts of cadmium in the diet can cause significant loss of bone mass in pregnant rats and ovariectomized rats, but cadmium in male rats and non-pregnant Female rats have little effect. It is well-known that tobacco contains heavy metals such as cadmium. In vitro experiments also found that the addition of cadmium to cell cultures significantly reduced bone formation. Epidemiologists have long proved that smoking is a risk factor for osteoporosis but so far