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纤维蜜蛋白是一种糖蛋白,存在于细胞表面,有粘附作用;它在血浆中起调理素作用,使颗粒状碎片和微生物易被吞噬。在严重病变及损伤时纤维蜜蛋白的减少伴有预后不良,尤在弥漫性血管内凝血(DIC)时。推测循环中纤维蜜蛋白的减少可导致有害物质的清除障碍,结果加重微循环及重要器官的损害。Mosher 等于1978年检测了36例患者血浆中的纤维蜜蛋白含量,发现纤维蜜蛋白降低者的死亡可能性明显高于正常量的患者。
Fibroin is a glycoprotein that is present on the cell surface and has an adhesive effect; it acts as an opsonin in the plasma that renders granular debris and microbes easily engulfed. Reduced fibrin in severe disease and injury associated with poor prognosis, especially in diffuse intravascular coagulation (DIC). It is hypothesized that the reduction of circulating fibroin in the circulation may result in the removal of harmful substances, resulting in increased microcirculation and damage to vital organs. Mosher et al. (1978) examined the plasma levels of fibrin in 36 patients and found that the probability of death from fibrinopathic patients was significantly higher than that of normal patients.