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本文研究抗甲状腺药物（ＡＴＤ）单独或与甲状腺激素联合应用，对Ｇｒａｖｅｓ病（ＧＤ）病情演变和转归的作用。联合用药组血清甲状腺刺激抗体（ＴＳＡｂ）下降的幅度明显大于单独应用ＡＴＤ组，其血清ＴＳＨ水平、药物性甲减的发病率以及停药后甲亢的复发率均显著低于单独用药组。提示ＡＴＤ与甲状腺制剂联合应用对ＧＤ具有更好的治疗效果。
This article studies the anti-thyroid drugs (ATD) alone or in combination with thyroid hormone on Graves disease (GD) the evolution and outcome of the disease. Serum thyroid stimulating antibody (TSAb) decreased significantly in combination group than in ATD group alone. Serum TSH levels, the incidence of drug hypothyroidism and the relapse rate of hyperthyroidism after drug withdrawal were significantly lower than those in the drug-alone group. Tip ATD and thyroid preparations in combination with the GD has a better therapeutic effect.