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目的：比较不同的生长抑素制剂（施他宁、奥曲肽）与垂体后叶素治疗肝硬化食管、胃底静脉曲张破裂出血的疗效。方法：将５２例出血患者随机分为３组，１５例予施他宁治疗，剂量为首次２５０μｇ静注，再以６０００μｇ／２４ｈ持续静滴；１５例予奥曲肽治疗，剂量为首次０．１ｍｇ静注，再以０．６ｍｇ／２４ｈ持续静滴；２２例予垂体后叶素３０Ｕ／８ｈ持续静滴，３组均连用３天。结果：施他宁组、奥曲肽组、垂体后叶素组平均止血时间分别为（１６±１１）、（２０±７）、（３７±３０）小时，３组间比较均有显著性差异（Ｐ＜０．０５）。施他宁组与奥曲肽组的疗效均优于垂体后叶素组。结论：施他宁、奥曲肽治疗肝硬化食管、胃底静脉曲张破裂出血的疗效较垂体后叶素好
OBJECTIVE: To compare the curative effect of different somatostatin preparations (sitotin, octreotide) and vasopressin in the treatment of hepatic cirrhosis with esophageal and gastric variceal bleeding. Methods: Fifty-two patients with hemorrhage were randomly divided into three groups. Fifteen patients were treated with shitamycin. The first dose of 250 mg intravenous injection followed by intravenous infusion of 6000 μg / Note, and then continued intravenous infusion of 0.6mg / 24h; 22 cases of pituitrin 30U / 8h continuous intravenous infusion, 3 groups were used for 3 days. Results: The mean hemostatic time of the group of shitamine, octreotide and pituitrin were (16 ± 11), (20 ± 7) and (37 ± 30) hours, respectively, with significant differences between the three groups (P <0.05). The effects of shituning group and octreotide group were better than that of pituitrin group. Conclusion: The effect of situtin and octreotide in the treatment of esophageal and variceal bleeding of cirrhosis is better than that of pituitrin