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解脲支原体与多种疾病有关,但引起疾病的确切机制尚不清楚。MB抗原是解脲支原体感染时被识别的主要外膜抗原,具有种特异性,包含血清型特异的和交叉反应的抗原决定簇。编码MB抗原的基因长1200多个碱基,N端1/3为保守区,包含群特异的抗原决定簇;C端2/3是由重复序列组成的可变区,包含型特异的抗原决定簇,对该抗原的研究及对于研究疾病的发病机制和免疫机制起重要作用。
Ureaplasma urealyticum and a variety of diseases, but the exact mechanism of the disease is not yet clear. The MB antigen is the major outer membrane antigen recognized by Ureaplasma urealyticum infection and is species specific and contains serotype specific and cross-reactive antigenic determinants. The gene encoding MB antigen is more than 1200 bases in length and the N-terminal 1/3 is a conserved region that contains group-specific antigenic determinants. The C-terminal 2/3 variable region consists of a repetitive sequence and contains a type-specific antigenic determinant Clusters, the study of the antigen and the study of disease pathogenesis and immune mechanisms play an important role.