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目的:观察采用硝苯地平联合卡托普利治疗高血压的临床疗效。方法:本组选取2011年5月～2012年5月我院收治的94例高血压患者,并将其随机分为两组,治疗组患者给予硝苯地平联合卡托普利进行治疗,对照组患者仅给予卡托普利或硝苯地平进行治疗。结果:两组均取得一定疗效,且均未见明显不良反应。其中,治疗组显效24例,有效18例,总有效率为89.4%;对照组显效15例,有效19例,总有效率为72.3%。治疗组疗效明显好于对照组,且差异明显,比较具有统计学意义(P<0.05)。结论:采用硝苯地平联合卡托普利治疗高血压,可有效地增加冠状动脉供血量及改善心脏功能,疗效显著,且不会引起各种严重性不良反应,因此,可作为持久治疗高血压比较理想的联合用药。
Objective: To observe the clinical efficacy of nifedipine combined with captopril in the treatment of hypertension. Methods: This group selected 94 patients with hypertension treated in our hospital from May 2011 to May 2012 and randomly divided them into two groups. The patients in the treatment group were treated with nifedipine and captopril, and the control group Patients were given only captopril or nifedipine for treatment. Results: The two groups have achieved a certain effect, and no significant adverse reactions. Among them, the treatment group markedly effective in 24 cases, effective in 18 cases, the total effective rate was 89.4%; control group markedly effective in 15 cases, effective in 19 cases, the total effective rate was 72.3%. The treatment group was significantly better than the control group, and the difference was statistically significant (P <0.05). Conclusion: Nifedipine combined with captopril treatment of hypertension, can effectively increase coronary blood supply and improve cardiac function, the effect is significant, and will not cause a variety of serious adverse reactions, therefore, can be used as long-lasting treatment of high The ideal combination of blood pressure medication.