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氨噻肟头孢菌素(HR756)是一种新的第三代头孢菌素,对许多革蓝氏阳性及阴性细菌,特别是肠杆菌科细菌呈现极高的抗菌活性。 国产HR756已由四川抗菌素工业研究所研制成功,并已开始临床试用,为了解HR756的体内过程,本文报 本品实验动物组织与体液中分布的特点,供临床参考。
Cefotaxime (HR756) is a new third-generation cephalosporin that exhibits high antibacterial activity against many gram-positive and -negative bacteria, especially Enterobacteriaceae. Domestic HR756 has been successfully developed by the Sichuan Institute of Antibiotics, and has begun clinical trials, in order to understand the process of HR756 in vivo, this article reports the characteristics of the experimental animal tissue and body fluids distribution for clinical reference.