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目的:探讨妊娠期感染外阴阴道假丝酵母菌病安全、有效的治疗方法。方法:将175例妊娠合并外阴阴道假丝酵母菌病患者随机分为治疗组和对照组两组,治疗组患者采用复方苦参洗剂冲洗外阴并灌洗阴道后,将克霉唑阴道泡腾片(150mg)塞入阴道后穹窿进行治疗。对照组患者采用苏打水清洗外阴并灌洗阴道后,将克霉唑阴道泡腾片(150mg)塞入阴道后穹窿进行治疗。连续治疗10天为1个疗程,观察比较两组患者的临床疗效。结果:治疗组患者临床总有效率显著高于对照组,各临床症状改善情况亦显著优于对照组,组间临床疗效比较差异具有统计学意义(P<0.05)。结论:采用复方苦参洗剂灌洗阴道结合克霉唑阴道泡腾片治疗妊娠合并霉菌性阴道炎疗效显著,安全性高,值得临床推广应用。
Objective: To investigate the safe and effective treatment of vulvovaginal candidiasis infection during pregnancy. Methods: One hundred and seventy-five cases of pregnancy with vulvovaginal candidiasis were randomly divided into treatment group and control group. The patients in the treatment group were treated with Compound Kushen Lotion to wash the vulva and lavage the vagina, Slice (150mg) into the vaginal fornix for treatment. Patients in the control group were treated with soda water to wash the vulva and lavage the vagina, then clotazole vaginal effervescent tablets (150mg) into the vaginal fornix for treatment. Continuous treatment of 10 days for a course of treatment, observed and compared the clinical efficacy of two groups of patients. Results: The total effective rate of the treatment group was significantly higher than that of the control group, and the improvement of clinical symptoms was also significantly better than that of the control group. There was significant difference in the clinical efficacy between the two groups (P <0.05). Conclusion: The compound Kushen lotion vaginal combined with clotrimazole vaginal effervescent tablets in the treatment of pregnancy complicated with fungal vaginitis significant effect, high safety, worthy of clinical application.