估计全世界将有3亿 HBsAg阳性携带者,且其中大多数无症状。 HBsAg携带状态是以病毒的活动性与宿主的免疫反应相互作用为特征的一种动态状况。在这一过程的早期,携带者通常为HBeAg阳性,且常有转氨酶水平升高。由于宿主的不同应答,有些无症状携带者在此早期阶段可有轻微的肝病、慢性迁延性肝炎(CPH)或慢性活动性肝炎(CAH),甚至肝 It is estimated that there will be 300 million HBsAg positive carriers worldwide, most of whom are asymptomatic. The state of HBsAg carriage is a dynamic condition characterized by the interaction of the virus’s activity with the host’s immune response. In the early stages of this process, carriers are usually HBeAg-positive and often have elevated levels of aminotransferases. Because of different host responses, some asymptomatic carriers may have mild liver disease, chronic persistent hepatitis (CPH) or chronic active hepatitis (CAH) at this early stage, and even liver