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目的:报告经单侧鼻孔入路显微手术治疗垂体腺瘤3例。2例指(趾)端肥大症,1例垂体瘤卒中,肿瘤最大2.4cm×1.9cm×1.8cm,最小1.0cm×0.8cm×0.4cm,2例嫌色细胞性腺瘤,1例嗜酸细胞性腺瘤。方法:均经CT或MR确诊,手术采取在一侧鼻前庭切口下方,增加鼻小柱斜切口,将鼻中隔推向一侧,保留鼻中隔四方软骨,经蝶窦打开鞍底切除肿瘤。结果:3例术后随访6月至2年均恢复正常生活和工作,CT复查未见肿瘤复发,内分泌检查均恢复良好。结论:垂体腺瘤采取经单鼻孔入路显微外科治疗是一种安全、有效的方法。
OBJECTIVE: To report three cases of pituitary adenoma treated by unilateral nostril approach. Two patients with acromegaly and one with pituitary apoplexy. The largest tumor was 2.4cm × 1.9cm × 1.8cm, the smallest was 1.0cm × 0.8cm × 0.4cm, 2 cases of chromophobe adenoma, 1 case of eosinophils Adenoma. Methods: All patients were diagnosed by CT or MR. Under the nasal vestibule incision, the incision was made to increase the columella oblique incision. The nasal septum was pushed to the side and the nasal septum was preserved. The sphenoid sinus was used to open the sellar tumor. Results: 3 cases were followed up from 6 months to 2 years and all of them returned to normal life and work. No recurrences of tumors were found after CT examination. Endocrine examinations all recovered well. Conclusion: It is a safe and effective method to treat pituitary adenomas by microsurgery through a single nostril approach.