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目的研究腹腔镜结直肠癌根治术的疗效及对胃肠功能的影响。方法选取2011年5月至2014年8月期间广东省东莞第八人民院收治的90例结直肠癌患者为研究对象,采取随机数字表法分为观察组和对照组,每组45例,观察组患者接受腹腔镜下手术,对照组患者接受开腹手术,比较两组患者手术情况、术后胃肠道功能恢复情况及术后并发症。结果两组患者手术时间、切除标本长度、淋巴结清扫数目比较差异无统计学意义(P>0.05)。观察组患者术中出血量少于对照组[(69.26±9.18)ml vs(119.48±14.26)ml](P<0.05),术后卧床时间短于对照组[(2.83±0.34)d vs(4.49±0.56)d](P<0.05)。观察组患者手术后的肛门排气时间、流质饮食开始时间短于对照组[(2.21±0.56)d vs(3.67±0.89)d,(3.89±0.79)d vs(6.01±1.02)d](P<0.05);术后3 d时,胃动素和胃泌素含量高于对照组[(249.52±31.38)pg/ml vs(152.42±20.49)pg/ml,(82.58±9.92)pg/ml vs(58.39±6.87)pg/ml(P<0.05)。观察组术后并发症明显低于对照组(24.44%vs 44.44%)(P<0.05)。结论腹腔镜结直肠癌根治术有助于减小手术创伤,促进术后恢复,改善胃肠功能,提高胃动素和胃泌素含量,减少术后并发症发生。
Objective To study the effect of laparoscopic radical mastectomy on gastrointestinal function. Methods Ninety patients with colorectal cancer admitted to the Eighth People’s Hospital of Dongguan, Dongguan City, Guangdong Province from May 2011 to August 2014 were selected as the research object. The random number table was divided into observation group and control group, with 45 cases in each group. The patients underwent laparoscopic surgery and the control group underwent laparotomy. The operation conditions, postoperative gastrointestinal function recovery and postoperative complications were compared between the two groups. Results There was no significant difference in the operation time, the length of resected specimens and the number of lymph node dissection between the two groups (P> 0.05). The bleeding volume in the observation group was less than that in the control group [(69.26 ± 9.18) ml vs (119.48 ± 14.26) ml] (P <0.05), and the postoperative bed stay was shorter than that in the control group [(2.83 ± 0.34) d vs ± 0.56) d] (P <0.05). The anal exhaust time after operation in the observation group was shorter than that in the control group [(2.21 ± 0.56) d vs (3.67 ± 0.89) d vs (3.89 ± 0.79) d vs (6.01 ± 1.02) d] <0.05). At 3 days after operation, the content of motilin and gastrin were higher than that of the control group [(249.52 ± 31.38) pg / ml vs (152.42 ± 20.49) pg / ml vs (82.58 ± 9.92) pg / ml vs (58.39 ± 6.87) pg / ml (P <0.05). Postoperative complications in the observation group were significantly lower than those in the control group (24.44% vs 44.44%, P <0.05). Conclusions Laparoscopic radical resection of colorectal cancer is helpful to reduce trauma, promote postoperative recovery, improve gastrointestinal function, increase motilin and gastrin, and reduce postoperative complications.