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目的探讨1.4%碳酸氢钠膀胱冲洗预防重症监护患者尿管相关的真菌性尿路感染的效果和方法。方法42例患者,随机分两组。预防组以1.4%碳酸氢钠膀胱冲洗,2次/d;对照组不行膀胱冲洗。并监测1.4%碳酸氢钠膀胱冲洗前后动脉血中剩余碱(BE)值的变化及尿常规中红细胞数的变化。结果1.4%碳酸氢钠膀胱冲洗可显著减少重症监护患者尿管相关的真菌性尿路感染发生率(P<0.01),1.4%碳酸氢钠膀胱冲洗前后动脉血中BE值及尿常规中的红细胞数的变化差异无统计学意义。结论1.4%碳酸氢钠膀胱冲洗可有效预防尿管相关的真菌性尿路感染,未见不良反应。
Objective To investigate the effect and method of 1.4% sodium bicarbonate bladder irrigation in preventing urinary tract associated fungal urinary tract infection in intensive care patients. Methods 42 patients were randomly divided into two groups. Prevention group with 1.4% sodium bicarbonate bladder irrigation, 2 times / d; control group not bladder irrigation. The change of residual base (BE) in arterial blood before and after bladder washing with 1.4% sodium bicarbonate and the change of red blood cells in urine were monitored. Results 1.4% sodium bicarbonate bladder flushing could significantly reduce the incidence of catheter-related fungal urinary tract infection (P <0.01) in intensive care patients, BE values in arterial blood before and after 1.4% sodium bicarbonate bladder irrigation and urine routine red blood cells The number of changes was not statistically significant. Conclusion 1.4% sodium bicarbonate bladder irrigation can effectively prevent the urinary tract associated fungal urinary tract infection, no adverse reactions.