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目的探讨男性不育与染色体异常的关系。方法按常规方法制作染色体标本,对3748例男性不育患者进行外周血淋巴细胞染色体核型分析。结果 3748例男性不育患者中,检出染色体异常502例,异常率为13.4%,其中性染色体异常359例,检出率为9.58%。结论染色体异常是导致男性不育的重要原因之一,对男性不育患者进行染色体核型分析很有必要。
Objective To investigate the relationship between male infertility and chromosomal abnormalities. Methods Chromosomal specimens were prepared according to the conventional methods, and the chromosomal karyotypes of peripheral blood lymphocytes were analyzed in 3748 male infertility patients. Results Of the 3748 cases of male infertility, 502 cases of chromosomal abnormalities were detected, the abnormality rate was 13.4%. There were 359 cases of chromosomal abnormalities with a detection rate of 9.58%. Conclusion Chromosomal abnormalities are one of the important causes of male infertility. It is necessary to analyze the karyotype of male infertility patients.