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目的:探讨东非合并支气管哮喘者的孕妇血维生素D水平与哮喘的关系。方法:根据哮喘程度将40例妊娠合并支气管哮喘患者分为轻度组16例、中重度组24例,同时选择20例健康者为对照组。检测哮喘患者与对照组的血维生素D水平及肺通气功能,并进行比较分析。哮喘患者用丙酸倍氯米松气雾吸入等治疗,中重度哮喘者加糖皮质激素静脉滴注。结果与结论:妊娠合并支气管哮喘患者的血维生素D水平显著降低,其水平与第1秒用力呼气量(FEV1)占预计值的百分比呈正相关。
Objective: To investigate the relationship between serum vitamin D levels and asthma in East African patients with bronchial asthma. Methods: According to the degree of asthma, 40 cases of pregnancy complicated with bronchial asthma were divided into mild group (16 cases) and moderate or severe group (24 cases). At the same time, 20 healthy controls were selected as control group. Blood levels of vitamin D and pulmonary ventilation were measured in patients with asthma and controls, and compared. Asthma patients treated with beclomethasone propionate aerosol inhalation, etc., moderate and severe asthma with glucocorticoid intravenous infusion. RESULTS AND CONCLUSION: The blood levels of vitamin D in pregnant women with bronchial asthma were significantly lower than those in the first trimester. The level of FEV1 was positively correlated with the predicted value.