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利用常规染色及Ｍｏｒｒｉｓ水迷宫对间隔１小时、连续３次５分钟脑缺血再灌流模型大鼠进行了行为学测试，并对实验鼠之海马进行了病理组织学观察。结果显示，海马ＣＡ１出现广泛的迟发性神经元坏死；行为学测试中，模型鼠训练潜伏期明显延长，提示其空间学习过程减慢、获得能力下降；但在空间探索试验中，模型鼠仍能在原平台象限游显著长的距离，提示其记忆能力并未受到明显损伤。其行为学改变应归因于ＣＡ１锥体细胞的减少。
The behavioral tests were performed on rats with cerebral ischemia and reperfusion 5 minutes apart and 1 hour intervals respectively by routine staining and Morris water maze. The hippocampus was observed histopathologically. The results showed that there was extensive delayed neuronal necrosis in hippocampal CA1. During the behavioral tests, the training latency of model mice was significantly prolonged, suggesting that the spatial learning process slowed down and acquired the ability to decline. However, in the space exploration test, In the original platform quadrant travel significantly longer distance, suggesting that its memory capacity has not been significantly damaged. The behavioral changes should be attributed to the reduction of CA1 pyramidal cells.