多发性骨髓瘤(简称MM),是浆细胞恶性增生所引起的肿瘤性疾病。解放以来迄1980年12月底止国内已有439例报道,男:女=2.2∶1,最大年龄79岁,最小11岁,大多数都在40岁以上。国内自1975年后由于开展了免疫球蛋白(简称Ig)的测定,对MM有了确切的分型,以及近几年来电子显微镜的检查,使这项研究已深入到细胞超微结构的水平。此外在该病的瘤细胞中,可见到各种非特异性的染色体异常。 Multiple myeloma (referred to as MM), is a neoplastic disease caused by malignant proliferation of plasma cells. Since liberation as of the end of December 1980 has been reported in 439 cases, male: female = 2.2: 1, the maximum age of 79 years old, the youngest 11 years old, most of them over 40 years of age. Since 1975, due to carry out the determination of immunoglobulin (Ig), the exact classification of MM, as well as in recent years, electron microscopy examination, the study has been deep into the level of cellular ultrastructure. In addition to the disease in the tumor cells, you can see a variety of non-specific chromosomal abnormalities.