新生儿肺透明膜病(HMD)是早产儿的主要并发症。外源性肺表面活性物质联合有创性机械治疗,效果已得到肯定,但机械通气后可造成多种相关性并发症,例如气压伤、呼吸机相关性肺炎、支气管发育不良等[1]。近年来无创通气倍受关注,经鼻持续正压通气(CPAP)与机械通气相比,合并症少,更 Neonatal hyaline membrane disease (HMD) is a major complication of preterm infants. Exogenous pulmonary surfactant combined with invasive mechanical treatment, the effect has been affirmed, but after mechanical ventilation can cause a variety of related complications, such as air pressure injury, ventilator-associated pneumonia, bronchial dysplasia [1]. In recent years, non-invasive ventilation has drawn much attention. Compared with mechanical ventilation, Nasal continuous positive pressure ventilation (CPAP) has fewer complications and more